In marijuana, which cannabinoids are psychoactive?

In marijuana, which cannabinoids are psychoactive?

• A. CBD is psychoactive.
• B. Neither CBD nor THC is psychoactive.
• C. Both THC and CBD are psychoactive.
• D. Only THC is psychoactive.

Answer: (D)

Psychoactivity in cannabis comes from compounds that cause changes in perception, mood, and consciousness by acting on brain receptors. The primary psychoactive cannabinoid is THC, which binds strongly to CB1 receptors in the brain and produces the characteristic high, along with effects on memory, attention, coordination, and mood. CBD, while a major constituent, does not produce intoxication because it has very low affinity for CB1 receptors and can even modulate the effects of THC without causing a high. So, among the common cannabinoids in marijuana, the one that reliably produces the psychoactive high is THC, making it the correct choice.

Psychoactivity in cannabis comes from compounds that cause changes in perception, mood, and consciousness by acting on brain receptors. The primary psychoactive cannabinoid is THC, which binds strongly to CB1 receptors in the brain and produces the characteristic high, along with effects on memory, attention, coordination, and mood. CBD, while a major constituent, does not produce intoxication because it has very low affinity for CB1 receptors and can even modulate the effects of THC without causing a high. So, among the common cannabinoids in marijuana, the one that reliably produces the psychoactive high is THC, making it the correct choice.