Name the endogenous cannabinoid neurotransmitter.

Name the endogenous cannabinoid neurotransmitter.

• A. Dopamine
• B. Serotonin
• C. Anandamide
• D. GABA

Answer: (C)

Anandamide is the endogenous cannabinoid neurotransmitter. Endocannabinoids are lipid-based signals produced on demand in the brain and act as retrograde messengers, binding to CB1 and CB2 receptors on presynaptic terminals to modulate the release of other neurotransmitters. Anandamide (N-arachidonoylethanolamine) is the best-known endogenous ligand for these receptors, with another endocannabinoid, 2-AG, also playing a role. Dopamine, serotonin, and GABA are classic neurotransmitters with different roles and signaling patterns, not the primary endogenous ligands for the cannabinoid system.

Anandamide is the endogenous cannabinoid neurotransmitter. Endocannabinoids are lipid-based signals produced on demand in the brain and act as retrograde messengers, binding to CB1 and CB2 receptors on presynaptic terminals to modulate the release of other neurotransmitters. Anandamide (N-arachidonoylethanolamine) is the best-known endogenous ligand for these receptors, with another endocannabinoid, 2-AG, also playing a role. Dopamine, serotonin, and GABA are classic neurotransmitters with different roles and signaling patterns, not the primary endogenous ligands for the cannabinoid system.